How to Stop Exenatide Without Rebound Weight Gain: What Patients Need to Know About Bydureon, Byetta, and Weight Regain

Exenatide helped define the modern GLP-1 era long before Ozempic became mainstream. This evidence-based review explains how exenatide worked, why Bydureon and Byetta were discontinued, and why stopping GLP-1 therapy often leads to rebound weight gain without a structured maintenance plan.