Semaglutide vs Tirzepatide vs Retatrutide: How the New Generation of Obesity Drugs Compare

Semaglutide, tirzepatide, and retatrutide represent three generations of obesity medications. Here’s how GLP-1, dual-agonist, and triple-agonist therapies compare for weight loss, metabolism, and future obesity treatment.

Retatrutide: The Triple-Target Weight Loss Drug That Could Redefine Obesity Treatment

Retatrutide is an investigational triple-agonist weight loss injection targeting GLP-1, GIP, and glucagon receptors simultaneously. Early trials suggest it may outperform current obesity medications, including Wegovy and Mounjaro.